https://www.soltlab.com/publications daily 0.75 2025-09-18 https://www.soltlab.com/ken-solt daily 0.75 2026-03-30 https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/1638f5e0-1880-494b-bb9d-5536932f4629/Ken+Solt.jpg Ken Solt - Ken Solt, MD Vice Chair of Research, Department of Anesthesiology, Mass General Brigham Edward Mallinckrodt Jr. Professor of Anaesthesia, Harvard Medical School Website | PubMed | Google Scholar https://www.soltlab.com/home daily 1.0 2026-03-30 https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/2943dbf6-1b4c-4747-90e9-a714ea59a6dd/Ken+Solt.jpg Home - Principal Investigator Ken Solt, MD Vice Chair of Research, Department of Anesthesiology, Mass General Brigham Edward Mallinckrodt Jr. Professor of Anaesthesia, Harvard Medical School https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/1602294159444-WOFUOBHW9LFXZ3ZUZZXD/Lab%2BDinner%2BMay%2B2018.jpg Home - Our Team We like to do cool science and eat good food together. Meet our current lab members, collaborators, and lab alumni. https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/1615319666712-9513Z7HFFBE3SW4ELWMQ/2020_08_03_RMTgM13_Vgat488_Cre594_Slide5_2-5X_Slice5_V1_c1_2_3+%281%29.jpg Home - Publications Read and download select publications from the Solt Lab. https://www.soltlab.com/research daily 0.75 2024-01-03 https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/329cb606-c6c7-4668-9a61-c1666199e428/Midbrain_yfpmcherry2.png Research - The Anesthetic Circuitry of the Midbrain How are cells in the midbrain involved in anesthetic-induced unconsciousness and recovery of consciousness? We tackle this question using a combination of electric, chemogenetic, and optogenetic techniques to activate various neuronal populations in anesthetized rodents. Understanding these mechanisms will lead to new methods for inducing rapid recovery from general anesthesia and aid the development of new anesthetics with fewer side effects. https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/1615325548541-EJ8ORW0B7NUEODIPZA16/Patient_19_Spectrogram%2Bcopy.jpg Research - Clinical Studies of Reanimation and Recovery from General Anesthesia Emergence from general anesthesia provides a unique window into the process of recovery from a comatose state to a conscious state, and our work will provide fundamental insights into how human cognition is restored after general anesthesia. Understanding the neural mechanisms that drive this process will lead us to new treatments for clinical problems with no available therapy, such as postoperative delirium and cognitive dysfunction, and disorders of consciousness and cognition due to brain injuries and neurodegenerative diseases. https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/8bb8b696-3308-495e-8cd1-fc263f313078/DREADDs_50x.png Research - Rodent Studies of Anesthetic Action As part of the Integrated Systems Neuroscience Studies of Anesthesia project, we will conduct rodent studies in conjunction with human, non-human primate, and mathematical modeling studies to decipher the neurophysiological mechanisms of the four most commonly used anesthetic drugs: propofol, sevoflurane, dexmedetomidine, and ketamine. https://www.soltlab.com/lab-members daily 0.75 2026-03-30 https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/d1b8c0b3-0398-45eb-819d-73a614536813/DSC02887.jpg Lab Members https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/e2c55a3d-7c06-499e-853b-7d83039ef697/DObert.jpg Lab Members https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/d727c5aa-417c-4f83-acff-f09eaa0568c9/OMoody.jpg Lab Members https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/1603228541197-EIUKC05U6C2ERV7N2JGA/RKato.jpg Lab Members https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/bfe15c91-db62-414a-9a4e-776ef39d51aa/headshot_ams.jpg Lab Members https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/1631205387648-ZZ2RZZ1R0N8XUZCAG8GD/VStewart.jpg Lab Members https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/1631205355232-IERYYFXC6RWS7G1OXCTC/EDillon.jpg Lab Members https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/ed206be2-d709-4000-8eac-4c2fba9180f5/OMallari.jpg Lab Members https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/1602277976520-RYM58EONL3QH5PP1V0J8/VArora.jpg Lab Members https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/781f0b33-7e3c-4b2e-9805-3df992cd6845/JPei.jpg Lab Members https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/1602278009201-C5SPPGCY37UD0SKAJUUG/KVlasov.jpg Lab Members https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/0819dc98-111d-4aa1-bc64-135197f1f5cd/LHobbs.jpg Lab Members https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/2b632ac3-07e6-4ada-a3eb-7143014cccf6/JGuidera.jpg Lab Members https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/d51b4a51-e670-475e-8f94-31120638451b/JLee.jpg Lab Members https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/d301ad0d-bf58-4608-9e6a-f8526c50ac83/JKenny.jpg Lab Members https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/1601787206165-SKIR9YPV2SVAQ66U0XND/JChemali.jpg Lab Members https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/9ec6a890-2008-43af-af56-9132df8730ac/MFettiplace.png Lab Members https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/1601938553685-XNFL60VGPHDS0KRZTJSY/AJCho.jpg Lab Members https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/2ebb6358-e969-42d8-9b9d-c2d0f1c7996e/20231110_jsa_kathleen_vincent_005+%281%29.jpg Lab Members https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/b3bf1be8-213e-44a4-9fa8-7d47d7b26188/IMG_1767_Original.jpeg Lab Members https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/ae279665-86ac-400d-a7a3-9d607449d8ea/med+school+photo.jpg Lab Members https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/db583357-8c40-4e20-b2a1-165dce648a9f/NNikbakht2.jpg Lab Members https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/6275b7f6-5937-4ce8-b359-441a489a76fe/DSC_5867.jpg Lab Members https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/fae3204f-d077-404d-bbad-315129fec7fc/JW2024Headshot.png Lab Members https://www.soltlab.com/contact-us daily 0.75 2022-01-06 https://www.soltlab.com/life-at-solt-lab daily 0.75 2025-08-08 https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/1763339676516-1P7Y3B23ZSU4NNQ56FE3/IMG_2615.jpg Life at Solt Lab https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/2ec3b73f-dcf7-4064-b629-15ff2616b260/IMG_2526.jpg.jpeg Life at Solt Lab Celebrating Ken's appointment as the Edward Mallinckrodt, Jr. Associate Professor of Anaesthesia in the Field of Pharmacology and Innovation at Harvard Medical School! Congrats, Ken! https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/69c1fcb4-fdac-4045-ba96-8a0391ee9141/IMG_2573.jpg.jpeg Life at Solt Lab Always great to catch up with a Solt Lab alumni, especially in beautiful Tuscany! Nice to see you, David! https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/1754683847231-JT289NRIXD4PJ37ST2MA/IMG_1780.jpg Life at Solt Lab Goodbye lunch for our awesome summer student Brian! Thank you for all your hard work, and best of luck with your studies! https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/1754684242728-J1IAX83G40N476N1BMW6/IMG_1594.jpg Life at Solt Lab Final presentation for our visiting medical student Isabella! Phenomenal job this summer, and good luck with the rest of medical school! Hope to see you back in Boston for residency! https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/c4b3ae26-1078-463d-9fe3-1179f7364705/LegalHarborside_20210802.jpg Life at Solt Lab Thank you for all your hard work, Emma and Victoria! Have a great rest of your summer, and good luck with your studies! https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/366a33de-94a8-4843-a4fe-b9aacc2265fc/LegalHarborsidedinner_20210802.jpg Life at Solt Lab Farewell dinner for our awesome summer students Victoria and Emma, and happy birthday to Risako and Lucy! Featuring Emma's first lobster roll!!! https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/67d4e9dd-6973-4caa-9ad5-f0cce4f243e2/JPEG+image+2.jpeg Life at Solt Lab SS21 Solt Lab https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/af0a9498-12c6-4823-8764-fad1d19d5eb5/JPEG+image.jpeg Life at Solt Lab Lunch at Pier 6: Welcome 2021 summer students Emma and Victoria, and congrats to Risako on her recent publication!! https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/1601937050039-639VOC963JGA4QE0CRF5/2019+Summer+group.jpeg Life at Solt Lab Summer 2019 with the Nehs lab https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/1601937049359-ML1ABD2B9CWIGI9AYXRB/Winter+2018+Dinner.jpeg Life at Solt Lab Winter 2018 Lab Dinner - Happy holidays from the Solt and Nehs labs! https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/1601937044799-737KJRPE8N2I8A5R4803/Lab+Dinner+May+2018.jpg Life at Solt Lab May 2018 Lab Dinner - Farewell Norm, Lauren, Ksenia, and Jenny! https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/1601937168478-FDB0RYHUGJCP3LQJ36ZN/group_photo.jpg Life at Solt Lab https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/1601937440999-VYGV58CO8SYEY4W7HF01/Solt+Lab+Photo+2017.JPG Life at Solt Lab Solt Lab 2017 https://www.soltlab.com/404 daily 0.75 2020-10-06 https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/1602021118444-DKEXQ4R7N4D5SN4NKNUY/mouse-3194768_1920.jpg 404: Page Not Found - 404: Page Not Found Oh no! 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Submit your abstracts, check out the speakers, and register here: https://www.grc.org/consciousness-anesthesia-and-evolutionary-biology-conference/2025/ Abstract submission deadline is December 29th! https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/b5a15163-821d-46ea-92f8-a7bd650b19b9/Lab+dinner.jpg News - Make it stand out Farewell dinner at Long Wharf for Dr. David Obert before he heads back to TUM in Munich and a warm welcome to our summer students! https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/a6a52d91-42a0-4996-aa54-39fec1723da9/Lab+group+photo+summer+2024.jpg News - Make it stand out Taking the ferry to the lab dinner! https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/e1affb6d-8cc2-4cce-bbda-2e3ea60d6d34/headshot_ams.jpg News - Make it stand out Fourth year medical student, Eric Smith, joins the lab through the FAER MSAER Summer Program, June 2024 https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/b3bf1be8-213e-44a4-9fa8-7d47d7b26188/IMG_1767_Original.jpeg News - Make it stand out Postdoctoral Fellow Dr. Jinyoung Choi, PhD joins the Solt Lab, June 2024 https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/c3572f99-3c86-498d-8051-595d13dd4224/Backup_of_VTA+estim+graphical+abstract.png News - Make it stand out Deep brain stimulation in the ventral tegmental area restores consciousness from sevoflurane-, dexmedetomidine-, and fentanyl-induced unconsciousness. Read the whole paper here. https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/613a1c8b-f495-453e-bcdf-ac2c8b2a3827/GRC+2023.png News - Make it stand out Inaugural “Consiousness, Anesthesia, and Evolutionary Biology” GRC at Stonehill College, MA https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/402249df-8400-4008-a2cd-ce0dcb57f787/DObert.jpg News - Make it stand out Research Fellow, Dr. David Obert, MD, joins the Solt Lab in January 2023 https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/7d360579-f28b-4f83-a391-72c8c25d00be/med+school+photo.jpg News - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/1625145553556-RUDKYDQPHQX3P1BCPEBF/VStewart.JPG News - Make it stand out Victoria G. Stewart, BS ‘22 https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/1625145582961-JSX0N7XOP0VD6PQ97T0P/EDillon.jpg News - Make it stand out Emmaline Dillon, BS ‘23 https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/1625088967956-YPK23W2DDSKGJCJZQO9R/JPEG+image.jpeg News - Make it stand out Welcome & celebratory lunch at Pier 6! https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/1625145774876-FJ9I1WTLB7YTDTU8PYPZ/MFettiplace.png News - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f78f5468f893516b122d500/1625145699569-BPZ02SCY54N46MT5XD8D/AJCho.jpg News - Make it stand out Whatever it is, the way you tell your story online can make all the difference.